Denmark improved their chances of reaching the finals thanks to Christian Eriksen's win from a penalty kick against ten-man England at Wembley Stadium.
England vs Denmark: Reaction as it is
England dominated most of the first half but the competition turned when Harry Maguire was fired in the 32nd minute for his second recordable offense at Kasper Dolberg. Thomas Delaney was fouled in the area by Kyle Walker and Eriksen passed Jordan Pickford to send the penalty.
The home team reunited at the time-out, and Mason Mount leveled up almost exclusively for Kasper Schmeichel to keep the header from the distance. Daniel Wass headed for Pione Sisto's cross as Denmark threatened for a second, but they had done well enough to jump the hosts into second place in Group A2.
Simon Hart, UK correspondent
The first home loss in two years brings England back to the world in a blow, three days after beating Belgium. Continuing Maguire's unhappy start to the season, his red card was the turning point after a brilliant first half hour, and with ten men, England faced a tough challenge, even if it required that super Schmeichel save to reject an equalizer Mountain.
Sture Sando, Danish correspondent
The game was not good but a great result for Denmark – a win at Wembley for the first time since 1983 and preventing one of the best teams in the world from scoring more than two goals. Denmark will remain in the A League for another expedition, with matches to be played against Iceland and Belgium in November.
Danish midfielder Christian Eriksen : “It feels special. Above all played 100 matches [for Denmark], also beating England at Wembley. Before the game, I knew we hadn't done this in 37 years. Standing here as a winner is extraordinary. ”
Declan Rice, England midfielder : ” To the expelled I thought we played really well and used the ball really well. Reece James and Mason Mount were making great chances for us, but we couldn't get the ball back. If we keep playing this way then we knew there would be a goal but then the red card and the game automatically turns in their favor ”
• England had won 20 of their last 21 home games before this defeat.
• Denmark have lost only twice in their last 40 games.
• Denmark kept a clean slate in six of their eight UEFA Nations League matches
• Christian Eriksen has scored 24 goals in his last 35 international games
• Simon Kjær and Christian Eriksen win 100th door in Denmark
England : Pickford; Walker, Coady, Maguire; James, Mount (Sancho 73), Rice (Henderson 76), Phillips, Maitland-Niles (Mings 36); Kane, Rashford (Calvert-Lewin 72)
Denmark : Schmeichel; Wass, Kjær, A Christensen (M Jørgensen 46), Skov (Mæhle 46); De laney, Eriksen, Højbjerg (Jensen 88); Braithwaite (Vestergaard 73), Dolberg (Sisto 37), Y Poulsen
Belgium welcomes England on Sunday, November 15, while Denmark hosts Iceland.